Scientific Program
07:30
Registration
08:50
Conference Opening & Welcome
Jan Rosner & Páll Karlsson - Conference Co-Chairs
09:00-10:30
Session I: Patient Stratification – From Phenotypes to Mechanisms
Moderator: Jan Rosner, Denmark
09:00-09:30
Stratifying neuropathic pain patients in clinical trials: the way forward
Ralf Baron
UKSH Universitätsklinikum Schleswig-Holstein, Germany
09:30-10:00
Can we infer neuropathic pain mechanisms from treatment responses? Insights from pharmacological and non-pharmacological trials
Nadine Attal
Ambroise Paré Hospital, Boulogne-Billancourt, France
10:00-10:30
Patient-reported outcomes in neuropathic pain studies: can they predict the response to treatment?
Didier Bouhassira
National Institut for Health and Medical Research (Inserm), France
10:30-11:00
Coffee Break, Exhibition & Poster Viewing
11:00-13:00
Session II: From Bench to Bedside - What`s wrong with neuropathic pain trials?
Moderator: Páll Karlsson, Denmark
11:00-11:30
Lost in translation: the main reason for failing clinical trials in neuropathic pain?
Per Hansson
Karolinska Institutet, Sweden
11:30-12:00
Can we improve the neuropathic pain trial?
Roy L Freeman
Harvard Medical School, USA
12:00-12:30
Placebo analgesia: implications for clinical practice and trial design
Ulrike Bingel
University Medicine Essen, University Duisburg-Essen, Germany
12:30-13:00
Panel Discussion
Per Hansson
Karolinska Institutet, Sweden
Roy L Freeman
Harvard Medical School, USA
Ulrike Bingel
University Medicine Essen, University Duisburg-Essen, Germany
13:00-14:00
Lunch Break, Exhibition & Poster Viewing
14:00-15:00
Session III: Young Investigators - FlashTalks
Moderators: Jan Rosner, Denmark & Páll Karlsson, Denmark - Conference co-Chairs
| Study the mechanism of increased excitability of A-type sensory neuron on peripheral neuropathic pain by computational modeling - Peter Kan, Canada | |
| Predictors of response to lacosamide in peripheral neuropathic pain; a randomized, double-blinded, placebo-controlled, phenotype-stratified trial - Malin Erika Carmland, Denmark | |
| Evaluation of CPL207-280, a GPR40 Agonist, for Neuropathy Management: Preclinical Insights - Michal Janiszewski, Poland | |
| Advanced Glycation End-Products as Potential Serum Biomarkers for Painful Diabetic Peripheral Neuropathy in Type 1 Diabetes - Marie Sjøgaard, Denmark | |
| The Beneficial Effects of Sodium Butyrate in the Management of Neuropathic Pain Induced by Paclitaxel in Mice - Mariarosaria Cuozzo, Italy | |
| Cutaneous Schwann Cells – More than just the Axon Clothing in Peripheral Neuropathy? - Xiaoli Hu, Denmark | |
| Antihiperalgesic Synergism of Nortriptyline-Tramadol and Nortriptyline-Ibuprofen Combinations in Hyperglycemic Rats Experiencing Neuropathic Pain - Maria Gicela Pérez-Hernández, Mexico | |
| Are Skin Fibroblasts Persistent Producers of Inflammatory Mediators of Pain in Patients with Diabetes and Painful Neuropathy? - Zahra Nochi, Denmark | |
| Pulsed Radiofrequency or Surgery for Anterior Cutaneous Nerve Entrapment Syndrome: Long-Term Results of a Randomized Controlled Trial - Tom ten Have, Netherlands | |
| Disentangling Spinal and Supraspinal Sensitization in Neuropathic Pain after Spinal Cord Injury - Joëlle Katharina Metzger, Switzerland | |
| Exploring Radiculopathy in Underserved Communities: A Focus on AANHPI Populations and Risk Factors - Anita Cheung, USA | |
| BHV-2100, A First-In-Class TRPM3 Antagonist for the Treatment of Neuropathic Pain - Thomas Voets, Belgium | |
15:00-15:30
Coffee Break, Exhibition & Poster Viewing
15:30-17:15
Session IV: Revisiting the Mechanism of Peripheral and Central Sensitization
Moderator: Jan Rosner, Denmark
15:30-16:00
Deciphering Synaptic Mechanisms in Neuropathic Pain
Alban Latremoliere
Johns Hopkins University, USA
16:00-16:25
SCIENTIFIC DEBATE: Two sides of the same coin – peripheral mechanisms are sufficient to explain the phenomena observed in “Central Sensitization”
Jordi Serra
King's College Hospital, UK
16:25-16:50
SCIENTIFIC DEBATE: Activity in C-chemo-nociceptors sensitizes spinal processing of A-fiber input: implications for evoked vs. ongoing pain
Martin Schmelz
Heidelberg University, Germany
16:50-17:15
SCIENTIFIC DEBATE: Crossfire including Q&A from audience, and closing statements
Jordi Serra
King's College Hospital, UK
Martin Schmelz
Heidelberg University, Germany
08:00
Registration
09:00-10:30
Session V: Small Fibers – Big Problems?
Moderator: Páll Karlsson, Denmark
09:00-09:30
Neuroimmune crosstalks and neuropathic pain
Michaela Kress
Medizinische Universität Innsbruck, Austria
09:30-10:00
Skin biopsy in painful neuropathies: the role of nerves and non-neuronal cells
Grazia Devigili
Fondazione IRCCS Istituto Neurologico Carlo Besta, Italy
10:00-10:30
Small fiber neuropathy: what have we learned from clinical trials?
Catharina Faber
Maastricht University Medical Centre, Netherlands
10:30-11:00
Coffee Break, Exhibition & Poster Viewing
11:00-13:00
Session VI: Neurophysiology & Neuroimaging – The Quest for a Pain Biomarker
Moderator: Jan Rosner, Denmark
11:00-11:30
Evoked Potentials – A Tool to Investigate Loss and Gain in the Nociceptive System?
Diana Torta
KU Leuven, Belgium
11:30-12:00
Pain-autonomic interaction: a surrogate marker for central sensitization?
Michèle Hubli
Balgrist University Hospital, Switzerland
12:00-12:30
Cortical Excitability – Insights into Neuropathic Pain Pathophysiology and Novel Therapeutic Target
Daniel Ciampi de Andrade
Aalborg University, Denmark
12:30-13:00
Deconstructing the Sensation of Pain: Insights from Neuroimaging
Katja Wiech
University of Oxford, UK
13:00-14:00
Lunch Break, Exhibition & Poster Viewing
14:00-15:00
Session VII: Lessons learned from human in-vitro models of neuropathic pain
Moderator: Páll Karlsson, Denmark
14:00-14:30
What can we learn about human neuropathies from pain in a dish models? (
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Theodore J Price
University of Texas at Dallas, USA
14:30-15:00
Pain-in-a-Dish: Lessons about Pain and Pain Resilience from hiPSC
Stephen Waxman
Yale University, USA
15:00-15:30
Coffee Break, Exhibition & Poster Viewing
15:30-16:00
Session VIII: The Road Ahead
Moderators: Jan Rosner, Denmark & Páll Karlsson, Denmark
15:30-16:00
Panel Discussion with Speakers
Daniel Ciampi de Andrade
Aalborg University, Denmark
Per Hansson
Karolinska Institutet, Sweden
Katja Wiech
University of Oxford, UK
Martin Schmelz
Heidelberg University, Germany
Grazia Devigili
Fondazione IRCCS Istituto Neurologico Carlo Besta, Italy
Catharina Faber
Maastricht University Medical Centre, Netherlands
Roy L Freeman
Harvard Medical School, USA
16:00
Best Abstract Award Announcement
16:10
Conference Closing Remarks
Jan Rosner, Denmark & Páll Karlsson, Denmark - Conference Co-Chairs
